Description_x000D_ General description_x000D_ Metoprolol has antihypertensive and anti-ischemic properties. It is used to treat arrhythmias._x000D_ Application_x000D_ (±)-Metoprolol (+)-tartrate salt has been used:_x000D_ • to modulate the immunological parameters in various studies_x000D_ • to study its effects onCa2+-calmodulin-dependent protein kinase II (CaMKII) activity in human and experimental heart failure (HF)_x000D_ • to examine the contribution of the adrenergic receptors to the production of norepinephrine (NE)-mediated O2-_x000D_ Biochem/physiol Actions_x000D_ β1-adrenoceptor antagonist._x000D_ Features and Benefits_x000D_ This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_ Other Notes_x000D_ Shelf-life of the powder is at least 4 years._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC