Description Application 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent. • It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64Cu radioisotope. • DOTA can be activated with N-hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy. • It can form complexes with gadolinium for application as MRI contrast agents. • Metal complexes of DOTA-peptide conjugates can be used as therapeutic radiopharmaceuticals. Packaging 50, 250 mg in poly bottle