Description General description 2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is a dialdehyde derivative. It has been synthesized by heating p-cresol with hexamethylenetetramine. The structure has been confirmed by 1H and 13C NMR. It is an important raw material for the synthesis of various binucleating schiff base ligand. Application 2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is suitable reagent used in the synthesis of 2-(2′-vinyloxyethoxy)-5-methylisophthaldehyde and chiral calixsalen macrocycles. 2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde may be used in the synthesis of the following: • 3-[(2,4-Dichlorophenyl)iminomethyl]-2-hydroxy-5-methylbenzaldehyde, a Schiff base. • 2-Hydroxy-3-methoxymethyl-5-methylbenzaldehyde. • Acyclic Schiff-base ligands. • Macrobicyclic ligands (MSB). • 4-Methyl-2,6-divinylphenol. • 2-Hydroxy-3-dimethoxymethyl-5-methylbenzaldehyde. Packaging 1 g in glass bottle