Description; General description; 5′-Bromo-2-deoxyuridine (BrdU) is a carcinogen that may be absorbed by skin or inhalation. BrdU solutions are sensitive to light.[1]; Application; 5-Bromo-2′-deoxyuridine has been used: • to label proliferating cells in pregnant mice in cell proliferation assay[3] • to study the time course of cell proliferation at various times following ischemia[4], to confirm re-entry of MKI67+ cells in cell cycle to germ cells[5] • in 5′-Bromo-2′Deoxyuridine (BrdUrd) staining of fibroblasts[6]; Packaging; 1 g in poly bottle; 50, 250 mg in poly bottle; Biochem/physiol Actions; 5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.; 5′-Bromo-2-deoxyuridine (BrdU) staining is predominantly used to observe the multiplication of tumor cells and other tissues in vivo.[2]; Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.