Description_x000D_ General description_x000D_ 6-Azauridine is a pyrimidine nucleoside analog._x000D_ Application_x000D_ 6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies._x000D_ 6-Azauridine has been used:_x000D_ • in uridine monophosphate synthase (UMPS) activity assay_x000D_ • as an antiviral agent to study its inhibition effect and cytotoxic potential on foot and mouth disease virus_x000D_ • to screen for anticryptosporidial activity_x000D_ • in the pretreatment of HeLa cells to study its effect on inhibition of cellular uridine synthesis before and during chase with 5-bromouridine 5′-triphosphate (BrUTP)_x000D_ • as a reference compound for comparing the antiviral activity and cytotoxic activity against viral host cell lines_x000D_ Packaging_x000D_ 1, 5 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ 6-azauridine is a prodrug, upon conversion to 6-aza-UMP, inhibits uridine monophosphate synthase (UMPS). It is a broad spectrum anti-metabolite. It interferes with pyrimidine biosynthesis and affects the cellular nucleic acid levels. It is considered as a antineoplastic metabolite. It inhibits RNA viruses like chikungunya virus, semliki forest virus, and human coronavirus. It significantly inhibits the growth of Cryptosporidium parasites.