Description_x000D_ Application_x000D_ 6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting._x000D_ Biochem/physiol Actions_x000D_ Glucocorticoid with slightly longer half-life than that of prednisolone._x000D_ Physical form_x000D_ Lyophilized containing ~5% phosphate buffer salts.