Description_x000D_ Application_x000D_ 7β-hydroxycholesterol was used to study oxysterol-induced apoptosis in human endothelial cells._x000D_ Packaging_x000D_ 1, 5 mg in glass bottle_x000D_ 10 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ 7β-Hydroxycholesterol is an oxysterol, the enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis._x000D_ Preparation Note_x000D_ 7β-Hydroxycholesterol yields clear, colorless to faint yellow solution in ethanol, with or without heating.