Description_x000D_ Application_x000D_ 8-Hydroxy-2′-deoxyguanosine has been used:_x000D_ • as a standard to analyse the oxidative DNA damage in the placenta of normal and abnormal pregnancies by electrochemical detection_x000D_ • as a standard for high performance liquid chromatography (HPLC) with electrochemical detection (ECD) measurement_x000D_ • as a standard for HPLC and as a urinary marker of oxidative stress in order to assess the potential antioxidant activity of green coffee bean extract (GCBE) in vivo_x000D_ • as a standard for LC/MS/MS analysis_x000D_ Packaging_x000D_ 1, 5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ A marker compound typically indicative of DNA damage associated with mutagenesis and carcinogenesis_x000D_ The levels of 8-hydroxy-2′-deoxyguanosine helps in evaluating oxidative stress and DNA damage in individuals suffering from laryngeal cancer. Hence it serves as a major biomarker of DNA damage, induced by reactive oxygen species (ROS).