Description General description Note: 1 MU = 1,000,000 units. Recombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential in chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer. Recombinant, human αA-interferon expressed in E. coli. Antiviral, anti-neoplastic agent. αA-Interferon exhibits therapeutic potential with chronic viral hepatitis, polycythemia vera, and various malignancies. It enhances natural killer cell activity, suppresses bone marrow function, and induces apoptotic cell death in non-melanoma skin cancer. NOTE: 1MU = 1,000,000 units. Packaging 5 mu in Plastic ampoule Warning Toxicity: Standard Handling (A) Unit Definition One unit of interferon per ml of medium will cause a 50% inhibition of VSV-induced cytopathic effect on bovine MDBK cells. Units are determined with respect to the NIH international reference standard for human αA-IFN. Dilute in aqueous buffer containing at least 0.1% BSA or HSA. Physical form In PBS containing 0.1% BSA. Preparation Note Dilute only in buffers containing protein such as 0.1% BSA. Reconstitution Following initial thaw, aliquot and freeze (-70°C). Other Notes Fujishima, H., et al. 1998. Int. J. Cancer 76, 423. Haria, M., and Benfield, P. 1995. Drugs 50, 873. Familletti, P.C., et al. 1981. Methods Enzymol. 78, 387.