Description_x000D_ General description_x000D_ α1-Antichymotrypsin (α1-ACT) is also known as serpin peptidase inhibitor, clade A member 3 (SERPINA3). It is a 68 kDa serine protease inhibitor, secreted by the liver. It belongs to the serpin superfamily of protease inhibitors. SERPINA3 is located on human chromosome 14q32.1._x000D_ Application_x000D_ α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays._x000D_ Biochem/physiol Actions_x000D_ Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons._x000D_ α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC)._x000D_ Packaging_x000D_ Package size based on protein content._x000D_ Physical form_x000D_ Lyophilized powder containing Tris buffer salt and NaCl.