Description_x000D_ General description_x000D_ Acetaminophen or paracetamol is an analgesic and antipyretic. It is however a weak non opioid analgesic._x000D_ Application_x000D_ Acetaminophen has been used:_x000D_ • as an anti-inflammatory drug to test its effect in lipid peroxidation in marine mussels_x000D_ • to test its effect on neurite outgrowth in gamma-aminobutyric acid-ergic and glutamatergic neurons_x000D_ • as a hepatocellular injury inducing agent in mice_x000D_ Analgesic._x000D_ Packaging_x000D_ 1 kg in glass bottle_x000D_ 100, 500 g in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Acetaminophen or paracetamol is an inhibitor of prostaglandin synthesis. It is complexed with arachidonic acid in central nervous system resulting in the formation of N-arachidonoylphentolamine, which is essential for the activation of cannabinoid receptor. Acetaminophen is metabolized to toxic N-acetyl-p-benzoquinone imine. Paracetamol is prescribed for osteoarthritis pain and inhibits cyclooxygenase 1 and 2 activities. It is metabolized by the cytochrome P450 enzymes in liver and is implicated in liver toxicity.