Description_x000D_ General description_x000D_ Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells._x000D_ Application_x000D_ Alantolactone has been used:_x000D_ • in cell viability assay_x000D_ • to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)_x000D_ • in assessment of degranulation_x000D_ Packaging_x000D_ 5, 25 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.