Description_x000D_ Application_x000D_ Antalarmin hydrochloride has been used:_x000D_ • to study its effect on stress-induced tryptophan hydroxylase 2 activity_x000D_ • to study the anxiogenic effects of corticotropin-releasing factor 1 (CRF1) activation_x000D_ • to analyze the therapeutic effect of blocking corticotrophin-releasing hormone (CRH) signaling in treating social stress-induced depression_x000D_ Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist._x000D_ Packaging_x000D_ 10, 50 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Antalarmin serves as a non steroidal inhibitor of pregnancy even during the early stages. It is known to delay parturition. It also prevents the development of gastric ulcers which arises in response to stress._x000D_ Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist._x000D_ Features and Benefits_x000D_ This compound is featured on the Corticotropin-Releasing Factor Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.