Description General description Archvillin is a muscle-specific isoform of Supervillin. Archvillin binds F-actin and is believed to be involved in myogenesis and muscle cell migration. Archvillin binds ERK and modulates ERK signaling in smooth cells of the aortas of ferrets. Rabbit anti-archvillin antibody binds to human, mouse, and rat archvillin. Immunogen synthetic peptide corresponding to amino acid residues 650-666 of human archvillin. The corresponding sequence is identical in mouse. Application Rabbit anti-archvillin antibody can be used for immunohistochemistry at 20-40 μg/mL using heat-retrieved tissue sections from human heart by biotin/ExtrAvidin-Peroxidase. The antibody can also be used for indirect immunofluorescence at 20-40 μg/mL using differentiated rat L8 cells. Furthermore, the antibody is suitable for use in western blot (2.5-5 μg/mL using whole extract of differentiated mouse C2 cells) assays. Physical form Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide Disclaimer Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.