Description_x000D_ General description_x000D_ Monoclonal Anti-β-Tubulin I (mouse IgG1 isotype) is derived from the SAP.4G5 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse. Tubulin is the major building block of microtubules, an intracellular cylindrical filamentous structure, that is present in almost all eukaryotic cells. Tubulin exists in all cells as a 100 kDa protein, which assembles from heterodimers of α-tubulin and β-tubulin; both have a molecular weight of 55 kDa and share considerable homology._x000D_ Immunogen_x000D_ synthetic peptide corresponding to the C-terminal sequence of ß-tubulin isotype I, conjugated to BSA_x000D_ Application_x000D_ Anti-β-Tubulin I antibody, Mouse monoclonal has been used in:_x000D_ • immunoblotting_x000D_ • immunofluorescence_x000D_ • immunohistochemistry_x000D_ Physical form_x000D_ Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ β-Tubulin I is also useful in deducing the role that different tubulin isotypes play in nerve development, function or maintenance.