Description_x000D_ Immunogen_x000D_ synthetic peptide corresponding to the third extracellular loop of human C-C chemokine receptor 1 (CCR-1), conjugated to KLH. The immunizing peptide has 80% homology with the rat gene and 85% homology with the mouse gene._x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide._x000D_ Biochem/physiol Actions_x000D_ CCR1 is a seven transmembrane protein that binds to macrophage inflammatory protein 1 alpha (MIP-1 alpha), monocyte chemoattractant protein 3 (MCP-3) and myeloid progenitor inhibitory factor-1 (MPIF-1). It has important role in protecting the host from inflammatory responses, viruses and parasites.