Description_x000D_ General description_x000D_ Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and can be cleaved by caspase-3 at multiple sites (D301, D371, D375, and D384) during apoptosis. The generation of cleaved PTEN (D301) is an indicator of apoptosis._x000D_ Immunogen_x000D_ Synthetic peptide derived from human PTEN protein with D301 cleaved site._x000D_ Physical form_x000D_ 0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.