Description_x000D_ General description_x000D_ Conserved oligomeric Golgi complex 5 (COG5), also known as CDG2I, GTC90 and GOLTC1, is a member of the conserved oligomeric Golgi (COG) complex. The complex is an evolutionarily conserved multisubunit protein COG complex. COG is composed of eight distinct subunits organized in two heterotrimeric groups, Cog2-Cog3-Cog4 and Cog5-Cog6-Cog7, which are linked by the dimeric group formed by Cog1 and Cog8._x000D_ Immunogen_x000D_ peptide corresponding to the C-terminal region of human COG5, conjugated to KLH. The corresponding sequence is identical in mouse, rat, canine and monkey COG5._x000D_ Application_x000D_ Anti-COG5 antibody produced in rabbit has been used in immunoblotting._x000D_ Physical form_x000D_ Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Conserved Oligomeric Golgi complex 5 (COG5) complex that regulates membrane trafficking and maintenance of Golgi glycosylation machinery in eukaryotic cells. Mutations in COG5 gene result in congenital disorder of glycosylation type 2I.