Description_x000D_ General description_x000D_ DCLK1 is a neuronal transmembrane enzyme that may regulate cortical development, nerve cell migration and microtubule polymerization. This enzyme is similar to DCX, but DCLK1 additionally functions as a Ca2+/calmodulin-dependent protein kinase that can phosphorylate myelin basic protein and itself . Anti-DCLK1 (C-terminal) antibody is specific for rat and mouse DCLK1. In immunoblotting, detection of the DCLK1 band is specifically inhibited by the DCLK1 immunizing peptide._x000D_ Immunogen_x000D_ synthetic peptide corresponding to a sequence located at the C-terminal of mouse DCLK1, conjugated to KLH. The corresponding sequence is identical in mouse DCLK1 isoform 2 and rat DCLK1._x000D_ Application_x000D_ Anti-DCLK1 (C-terminal) antibody is suitable for use in western blot (0.05-0.1 μg/mL using S1 fraction extracts of postnatal (PN3) mouse brain) and immunoprecipitation (3-6 μg using S1 fraction extracts of postnatal (PN3) rat brain)._x000D_ Physical form_x000D_ Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.