Description_x000D_ General description_x000D_ By immunoblotting and ELISA, the antibody shows ~50% cross-reactivity with recombinant human ephrin-B5 and 15% cross-reactivity with mouse ephrin-B1._x000D_ Immunogen_x000D_ recombinant mouse ephrin-B2, expressed in NSO cells._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4 with 5% trehalose._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Ephrin B2 binds to EPH receptor B, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.