Description_x000D_ General description_x000D_ Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3._x000D_ Immunogen_x000D_ Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4._x000D_ Application_x000D_ Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry._x000D_ Target description_x000D_ Receptor for VEGFC. Has a tyrosine-protein kinase activity._x000D_ Physical form_x000D_ Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.