Description; General description; FOXC2 belongs to the forkhead transcription factor family and has a distinct DNA-binding forkhead domain. Increased expression of FOXC2 is known to prevent hypertriglyceridemia and insulin resistance induced by diet. FOXC2 has also been implicated in the metastasis of breast cancer. Rabbit Anti-FOXC2 antibody recognizes human, mouse, and canine FOXC2.; Immunogen; Synthetic peptide directed towards the middle region of human FOXC2; Application; Rabbit Anti-FOXC2 can be used for western blot applications at a concentration of 1.25μg/ml.; Physical form; Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.; Disclaimer; Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.; Biochem/physiol Actions; FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.; Sequence; Synthetic peptide located within the following region: VIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHA