Description_x000D_ General description_x000D_ FZD3 belongs to the frizzled (Fz) family. Frizzled homolog protein (FZD) is a seven-pass transmembrane type receptor expressed in various normal tissues (skeletal muscle, kidney, pancreas, cerebellum and cerebral cortex). In human, ten members (FZD1-FZD10) of Frizzled homolog protein have been identified. It is expressed in several cancers (esophageal carcinoma, lung squamous cell carcinoma, primary acute and lymphoblastic leukemia, myeloma, lymphoma and Ewing sarcoma)._x000D_ Immunogen_x000D_ synthetic peptide corresponding to the N-terminal extracellular domain of human frizzled-3, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene._x000D_ Application_x000D_ Anti-Frizzled-3 antibody is suitable for western blot analysis. It is also suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections) at a concentration of 5μg/mL, using human skeletal muscle._x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.