Description_x000D_ General description_x000D_ GrpL is a SH2- and SH3-domain containing adaptor protein that regulates tyrosine kinase signaling in leukocytes. This adaptor protein associates with SLP-76 and subsequently enhances NF-AT activation in T cells. GrpL also interacts with gab-1 . Monoclonal Anti-GrpL/GADS antibody is specific for human and mouse GrpL._x000D_ Immunogen_x000D_ fusion protein expressing human GrpL._x000D_ Application_x000D_ Monoclonal Anti-GrpL/GADS antibody is suitable for use in western blot (0.5-1.0 μg/mL using whole extracts of human Jurkat cells), immunoprecipitation and flow cytometry._x000D_ Physical form_x000D_ Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.