Description_x000D_ General description_x000D_ Transferrin is a bilobed glycoprotein. The polypeptide chain of transferrin is composed of two homologous lobes i.e N- and C- lobes. Each lobe is made of two domains N1, N2 and C1, C2 which are linked by a hinge. It has two specific sites for binding of Fe3+._x000D_ Application_x000D_ Anti-Transferrin antibody has been used:_x000D_ • in quantitative precipitin assay_x000D_ • in enzyme linked immunosorbent assay (ELISA)_x000D_ • in western blotting_x000D_ • in immunoblotting_x000D_ Anti-Transferrin antibody produced in goat was used in western blotting analysis of HEK293 cell extracts._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Transferrin is the major iron transporter protein that binds Fe(+3). The transferring-iron import system consists of a TonB dependent transporter (TbpA), and a lipoprotein co-receptor (TbpB) and both proteins work together in the transport of iron across the membrane._x000D_ Transferrin plays a major role in providing iron as a source for haemoglobin synthesis. It binds to the transferrin receptor 1(TfR1)._x000D_ Preparation Note_x000D_ treated to remove lipoproteins