Description_x000D_ General description_x000D_ The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells. (provided by RefSeq)_x000D_ Immunogen_x000D_ ICT1 (NP_001536.1, 1 a.a. ~ 206 a.a) full-length human protein._x000D_ Sequence_x000D_ MAATRCLRWGLSRAGVWLLPPPARCPRRALHKQKDGTEFKSIYSLDKLYPESQGSDTAWRVPNGAKQADSDIPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMD_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4