Description_x000D_ General description_x000D_ Human Interferon-γ- Receptor I (IFN-γ RI) is a 25kD, 227 amino acid residue containing protein that belongs to type II cytokine receptor family. IFN-γ RI has a crucial role in ligand-binding and signaling. Ligand IFN-γ induces tyrosine phosphorylation in IFN-γ RI which in turn leads to the formation of a docking site on the activated receptor for Stat1 that specifically activates IFN-γ induced gene transcription. Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in neutralization assay using a confluent culture of HeLa cells. Goat anti-Interferon γ Receptor I (IFN-γ RI) antibody reacts specifically with recombinant human IFN-γ RI. The product has shown no cross-reactivity for recombinant human IFN-γ RII._x000D_ Immunogen_x000D_ recombinant human IFN-γ Receptor I extracellular domain expressed in NSO cells._x000D_ Application_x000D_ Anti-Interferon γ Receptor I (IFN-γ RI) antibody can be used in indirect ELISA and western blot._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.