Description_x000D_ General description_x000D_ Anti-Keratin 17 antibody detects endogenous levels of total Keratin 17 protein._x000D_ Keratin 17/cytokeratin 17 (CK17) is a basal/myoepithelial cell keratin. It is expressed in the respiratory tract, urinary tract and various glands. CK17 is a member of the acidic type I CK family. It is mapped to human chromosome 17q21._x000D_ Immunogen_x000D_ The antiserum was produced against synthesized peptide derived from human Keratin 17._x000D_ Immunogen Range: 381-430_x000D_ Application_x000D_ Anti-Keratin 17, C-Terminal antibody has been used in immunohistochemical staining._x000D_ Physical form_x000D_ Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Keratin 17/cytokeratin 17 (CK17) plays a major role in the development of various human malignancies. It acts as a biomarker in endocervical glandular neoplasia. CK17 is involved in the development of cell and sizing of keratinocytes._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.