Description_x000D_ General description_x000D_ Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20._x000D_ Specificity_x000D_ Reacts with reduced and native MMP-24. Recognizes the pro-form of MMP-24 as well as activation/breakdown products._x000D_ Immunogen_x000D_ synthetic peptide corresponding to the hinge region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5)._x000D_ Physical form_x000D_ Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide._x000D_ Biochem/physiol Actions_x000D_ Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.