Description_x000D_ General description_x000D_ Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) possesses 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase activity. The gene encoding this protein is localized on human chromosome 14q23.3._x000D_ Immunogen_x000D_ Peptide with sequence RGDLNDCFIPCTPK from the internal region of the protein sequence according to NP_005947.2._x000D_ Physical form_x000D_ Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin._x000D_ Biochem/physiol Actions_x000D_ Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) has a role in folate-mediated one-carbon metabolism. It is involved in the conversion of formate and tetrahydrofolate to 5, 10-methylenetetrahydrofolate._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.