Description_x000D_ General description_x000D_ Munc-18 interacting protein 1 (Mint1) is an adaptor protein primarily localized in the brain. It possesses phosphotyrosine-binding (PTB) domains and PDZ (PSD95, Dlg1 and zo-1) domains which are common to its family._x000D_ Specificity_x000D_ Detects rat munc-18 interacting protein 1 (mint1) using rat brain extract and extract from HEK293 cells overexpressing the rat gene._x000D_ Immunogen_x000D_ synthetic peptide corresponding to amino acid residues 1-17 from rat mint1._x000D_ Physical form_x000D_ Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide._x000D_ Biochem/physiol Actions_x000D_ Munc-18 interacting protein 1 (Mint1) binds to amyloid-β precursor protein (APP) and also associates with calcium/calmodulin-dependent serine protein kinase (CASK).