Description_x000D_ Immunogen_x000D_ Immunogen Sequence: GI # 10835177, sequence 432-499_x000D_ Recombinant nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)_x000D_ Application_x000D_ Anti-NFKB1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200._x000D_ Physical form_x000D_ Solution in phosphate buffered saline containing 0.02% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Nuclear factor NF-κ-B p105 subunit is a protein encoded by the NFKB1 gene in humans. It is a DNA binding subunit of B-cell protein that interacts with the immunoglobulin κ light-chain gene enhancer. Tumor necrosis factor α (TNF α) helps in activation and induces expression of NFKB1 gene. Oxaliplatin reactivates HIV-1 expression by inducing nuclear factor κ B (NF-κB) nuclear translocation and may be a potential drug candidate for anti-latency therapies.