Description_x000D_ General description_x000D_ NAD(P)H quinone dehydrogenase 1 (NQO1) is an obligate two-electron reductase. It is a cytoplasmic, homodimeric protein, with one FAD molecule per monomer. The protein is expressed in many tissues. The NQO1 gene is localized to human chromosome 16q23._x000D_ Immunogen_x000D_ Peptide with sequence C-SIPTDNQIKARK from the C Terminus of the protein sequence according to NP_000894.1; NP_001020604.1; NP_001020605.1._x000D_ Physical form_x000D_ Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ NAD(P)H quinone dehydrogenase 1 (NQO1) is thought to confer protection against natural and exogenous quinones. It is involved in the conversion of benzene derived quinones to less toxic hydroquinones and also participates in benzene-associated hematotoxicity. This protein is also involved in the reduction and eventual activation of few chemotherapeutic drugs and carcinogens. NQO1 is up-regulated in serous ovarian carcinoma._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.