Description_x000D_ General description_x000D_ The CXC chemokine receptor 4 (CXCR4) is a G-protein coupled 7-transmembrane (TM) chemokine receptor. It is made up of 352 amino acids. CXCR4 is expressed on the surface of T-cells, B-cells, monocytes, neutrophils and dendritic cells. This gene is located on human chromosome 2q22.1._x000D_ Immunogen_x000D_ The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339._x000D_ Immunogen Range: 303-352_x000D_ Application_x000D_ Anti-phospho-CXCR4 (pSer339) antibody has been used in immunohistochemical analysis._x000D_ Physical form_x000D_ Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ The CXC chemokine receptor 4 (CXCR4) participates in the progression of the embryo, immune and inflammatory responses, modulation of hematopoiesis, human immunodeficiency virus infection and stimulation of angiogenesis. CXCR4 and its ligand, CXCL12 is involved in the synthesis of B-cell, myelopoiesis, integrin activation and chemotaxis._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.