Description_x000D_ General description_x000D_ FGFR1 (fibroblast growth factor receptor 1) gene codes for nine isoforms of FGFR1. It has 19 exons spanning 55kb DNA. It is located on human chromosome 8p11.1. Increased expression of FGFR1 is seen in midfacial membranous ossification sites. It is mostly present in hippocampal and dentate gyrus neurons._x000D_ Immunogen_x000D_ The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr154._x000D_ Immunogen Range: 121-170_x000D_ Physical form_x000D_ Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ FGFR1 (fibroblast growth factor receptor 1) helps in the growth of the nervous system. This gene controls the skeletal development and bone homeostasis. FGFR1 mutations lead to craniosynostosis and facial abnormalities. Mutation in FGFR1 Ig-like domain II-III linker region (FGFR1 P252R) results in Pfeiffer syndrome._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.