Description_x000D_ Immunogen_x000D_ Peptide sequence around aa. 574-578/575-579 (T-Y-Y-K-A), according to the protein PTK2._x000D_ Target description_x000D_ Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity._x000D_ Physical form_x000D_ Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol_x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.