Description_x000D_ General description_x000D_ Anti-Retinoic Acid Receptor α Antibody detects endogenous levels of total Retinoic Acid Receptor α protein._x000D_ Retinoic acid receptor α (RARα) is a nuclear receptor for retinoic acid and is expressed in the retina. It belongs to the nuclear steroid/thyroid hormone receptor superfamily. The gene encoding it is localized on human chromosome 17q21._x000D_ Immunogen_x000D_ The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor alpha._x000D_ Immunogen Range: 46-95_x000D_ Physical form_x000D_ Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Retinoic acid receptor α (RARα) is a ligand-dependent transcriptional modulator of genes that has a role in differentiation, cellular development and apoptosis. It has a role in germ-cell development in testis. The protein may be associated with acute promyelocytic leukemia._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.