Description_x000D_ General description_x000D_ The gene ubiquitin-like modifier activating enzyme 5 (UBA5) is mapped to human chromosome 3q22. It belongs to the E1-like ubiquitin-activating enzyme family. UBA5 transcripts are widely expressed in human tissues. The protein localizes in the cytoplasm and the nucleus._x000D_ Immunogen_x000D_ Synthetic peptide directed towards the middle region of human UBA5_x000D_ Application_x000D_ Anti-UBA5 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml._x000D_ Physical form_x000D_ Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Ubiquitin-like modifier activating enzyme 5 (UBA5) acts on the high-energy thioester bond and activates ubiquitin-fold modifier-1 (UFM1) that is involved in post-translational modifications of proteins. UBA5 is also responsible for activation of SUMO2 (Small ubiquitin-related modifier 2). Activity of UBA5 is critical for differentiation of erythrocytes._x000D_ Sequence_x000D_ Synthetic peptide located within the following region: VLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACF