Description_x000D_ General description_x000D_ Zinc finger protein 397 (ZNF397) belongs to the Cys2His2 group of the zinc-finger superfamily. It possesses a leucine-rich SCAN domain and nine Cys2His2 zinc fingers. The gene encoding this protein is localized on human chromosome 18q12._x000D_ Immunogen_x000D_ ZNF397 (NP_115723.1, 1 a.a. ~ 275 a.a) full-length human protein._x000D_ Sequence_x000D_ MAVESGVISTLIPQDPPEQELILVKVEDNFSWDEKFKQNGSTQSCQELFRQQFRKFCYQETPGPREALSRLQELCYQWLMPELHTKEQILELLVLEQFLSILPEELQIWVQQHNPESGEEAVTLLEDLEREFDDPGQQVPASPQGPAVPWKDLTCLRASQESTDIHLQPLKTQLKSWKPCLSPKSDCENSETATKEGISEEKSQGLPQEPSFRGIKLSRPPKASSAIRWECVSPGSFPGDIIAAEATHSTISCFAINTLPATILPSKNVNRKYFS_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4_x000D_ Biochem/physiol Actions_x000D_ Zinc finger protein 397 (ZNF397) has been shown to co-localize with centromere protein-A (CENP-A) during early prophase and interphase. It might be involved in transcriptional regulation.