Description General description Benzoyl chloride, an acid chloride, is a commonly used benzoylating agent. The arylation of 1,1- and 1,2-disubstituted activated alkenes using benzoyl chloride in the presence of palladium catalyst has been investigated. Application Benzoyl chloride may be used to synthesize: • 4-Methoxybenzophenone via acylation of anisole in the presence of cesium-substituted dodecatungstophosphoric acid (Cs2.5H0.5PW12O40) supported on K-10 clay. • Benzoylamino acids via acylation of amino acids in the presence of diisopropylethylamine. • p-, o-, m-Methylbenzophenones via benzoylation of toluene in the presence of Al-promoted sulfated zirconia catalysts. Packaging 1 L in PVC-coated bottle 1, 2.5, 4 L in glass bottle 25 mL in glass bottle Legal Information ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC