Description_x000D_ General description_x000D_ Beta Amyloid (1-42), ultra pure, TFA._x000D_ MOL. WT.: 4514.5 Da by Mass Spec Analysis (theoretical 4514.10)_x000D_ SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe- Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH_x000D_ PEPTIDE CONTENT: 1 mg per vial; salt content is <10%_x000D_ COUNTER ION: TFA_x000D_ Application_x000D_ Different researchers claim enhanced activity due to different salts._x000D_ The TFA salt is what has been the industry standard._x000D_ The HFIP makes the beta-amyloid homogenously monomeric._x000D_ The NaOH apparently make it monomeric too and is also water soluble, which the TFA salt and HFIP are not._x000D_ The HCl salt is supposed to be more biological, as TFA is not found in the body._x000D_ By offering the different salts, it lets the researchers duplicate the different assays that have been developed by other researchers (see below)._x000D_ TFA: Shu-chuan Jao, S-C, et. al. 1997, Amyloid; Int J Exp. Clinical Invest. 4, 231_x000D_ HFIP: Stine, W.B. et. al. 2003, J. Biol. Chem, 278, 11612_x000D_ NaOH: Fezoui, Y., et. al. 2000, Amyloid, 7, 166_x000D_ HCL: Kanek, I and Tutumi, S., 1997, J. Neurochem, 68, 438_x000D_ Research Category_x000D_ Neuroscience_x000D_ Research Sub Category_x000D_ Neurodegenerative Diseases_x000D_ Physical form_x000D_ White lyophilized powder. Resuspend in any one of the following solvents: 0.1% TFA, 5 mM HCl, 2 mM NaOH, 1.0 % NH4OH at a concentration of 1 mg/mL. Sonicate for 30 seconds to 1 minute after it has gone into solution. To bring into your solution: After resuspension, add 5x or 10x buffer stock (PBS, TBS) and water to bring to 1x buffer._x000D_ Storage and Stability_x000D_ Maintain lyophilized material at -20ºC for up to 12 months after date of receipt. After reconstitution maintain at -20ºC to -70ºC for up to 2 weeks in undiluted aliquots. Avoid freeze/thaw cycles to avoid aggregation._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.