Description_x000D_ Packaging_x000D_ 25, 50 mL in glass bottle_x000D_ Application_x000D_ Technical Article Comparing Performance of Different Enzymes_x000D_ Learn more_x000D_ about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine._x000D_ Biochem/physiol Actions_x000D_ β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain._x000D_ Unit Definition_x000D_ One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay)._x000D_ Physical form_x000D_ Supplied as an aqueous solution containing L-proline, ammonium acetate and sodium azide