Description_x000D_ General description_x000D_ β-Lactamase (β-lactamase, βL, EC 3.5.2.6) is an enzyme first identified in Escherichia coli and has been described as penicillinase. A number of βLs have since been identified from various bacteria. β-Lactamases specifically hydrolyze β-lactam rings present in antibiotics such as penicillin, cephalosporins, monobactam, and carbapenem, and confer resistance against these antibiotics._x000D_ Application_x000D_ Beta-Lactamase Inhibitor Screening Kit has been used in enzymatic assays._x000D_ Features and Benefits_x000D_ Compatible with high-throughput handling systems._x000D_ Suitability_x000D_ Suitable for the screening of inhibitors of β-Lactamase_x000D_ Principle_x000D_ The β-Lactamase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for high throughput screening of β-Lactamase inhibitors. βL activity is measured by hydrolyzing a chromogenic cephalosporin called nitrocefin, producing a colorimetric product (A490), proportional to the enzymatic activity present.