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BETA-SECRETASE INHIBITOR
Кат. №: S4562-1MG
Производитель: Sigma-Aldrich
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Цена по запросу
Товар оформляется под заказ
Печать
BETA-SECRETASE INHIBITOR
Кат. №: S4562-1MG
Производитель: Sigma-Aldrich
Кол-во:
Цена по запросу
Товар оформляется под заказ
Кол-во:
Цена по запросу
Товар оформляется под заказ
Description_x000D_
Amino Acid Sequence_x000D_
Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe_x000D_
General description_x000D_
β-Site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1), an aspartic protease belongs to the protease family of enzymes comprises of six luminal cysteine residues. These residues help in the formation of three intermolecular disulfide bonds and N-linked glycosylation sites._x000D_
Application_x000D_
β-Secretase inhibitor has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay.(2)_x000D_
β-Secretase inhibitor may be used to inhibit BACE1 in studies related to AD._x000D_
Biochem/physiol Actions_x000D_
β-Site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) is a β-secretase that initiates the production of amyloid protein in Alzheimer′s dieases (AD) patients. β-Secretase inhibitors decrease the generation of β amyloid and formation of amyloid plaques typical of AD.
Related Categories
β-Secretase, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Neurodegenerative Disease Peptides, Neuropeptides, Other Alzheimer’s Peptides, Peptides and Proteins, Peptides for Cell Biology, Protease Inhibitor Specificity Index, Protease Inhibitors, R to Z, S, beta-SecretaseMore... Quality Level
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