Description General description A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 > 100 µM). Blocks the activation of p70s6k/p85s6kin vivo (IC50 = 8 µM). A cell-permeable negative control compound for protein kinase C inhibition studies (IC50 >100 µM). Blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6kin vivo (IC50 8 µM). Packaging 1 mg in Plastic ampoule 400 μg in Plastic ampoule Biochem/physiol Actions Cell permeable: yes Primary Target Negative control compound for protein kinase C inhibition Product does not compete with ATP. Reversible: no Target IC50: >100 µM as negative control compound for protein kinase C inhibition; 8 µM in blocking the activation of mitogen-stimulated protein kinase p70s6k/p85s6k in vivo Warning Toxicity: Standard Handling (A) Other Notes Marmy-Conus, N., et al. 2002. FEBS Lett. 26094 (In Press) 1-6. Davis, P.D., et al. 1992. J. Med. Chem.35, 177. Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.