Description_x000D_ General description_x000D_ BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains._x000D_ Physical form_x000D_ Sterile filtered and Lyophilized without additives._x000D_ Reconstitution_x000D_ Centrifuge the vial prior to opening. Avoid freeze-thaw cycles._x000D_ Reconstitute to 0.1-1.0 mg/mL in water containing BSA (50 μg BSA per 1 μg of protein).