Description General description (Bromodifluoromethyl)trimethylsilane (TMSCF2Br) is commonly used as a source to generate dilfluorocarbene. TMSCF3 (Ruppert–Prakash reagent) and BBr3 undergoes fast halogen–exchange reaction to form MSCF2Br. Application (Bromodifluoromethyl)trimethylsilane may be used in the preparation of: • gem-difluorocyclopropa(e)nes • O-, S-, N-, and P-difluoromethylated compounds • (chlorodifluoromethyl)trimethylsilane As reported by Hu and co-workers, (Bromodifluoromethyl)trimethylsilane is a highly useful reagent for the formation of difluoromethene-containing 3-membered rings and can also difluoromethylate heteroatoms with the assistance of alkaline bases, most effectively KOH. Packaging 1 g in glass bottle Other Notes Prof. Jinbo Hu′s Professor Product Page Synthesis of gem-Difluorocyclopropa(e)nes and O-, S- N- and P-Difluoromethylated Compounds with TMSCF2Br