Description_x000D_ Application_x000D_ Functional Genomics/Screening/Target Validation_x000D_ • Positive control, HPRT1, CRISPR lentivirus DNA format, for creating gene knockouts/genetic modifications in cell lines._x000D_ To see more application data, protocols, vector maps visit Sigma.com/crispr._x000D_ Features and Benefits_x000D_ Serves as a positive experimental control for the CRISPR editing workflow using lenti CRISPR DNA. The number of cells with HPRT1 knocked out increases over time with 6−TG selection._x000D_ Physical form_x000D_ The Sigma CRISPR Lenti Human HPRT1 Positive Control Vector is provided as 1 μg of plasmid DNA in Tris−EDTA (TE)._x000D_ Legal Information_x000D_ CRISPR Use License Agreement_x000D_ Lentiviral and WPRE License Agreements