Description_x000D_ Application_x000D_ Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants._x000D_ Cyclic adenosine diphosphate-ribose has been used to stimulate astrocytes to activate CD38 signaling. It has also been used as a supplement in buffered peptone water to recover S. enteritidis._x000D_ Packaging_x000D_ 0.5 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+ release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants._x000D_ Packaging_x000D_ Package size based on nucleotide content._x000D_ Physical form_x000D_ Lyophilized powder containing approx. 30% sodium phosphate buffer salts.