Description_x000D_ General description_x000D_ D-Mannitol is the alcohol form of mannose. Its molar mass is 182 g/mol. Mannitol is present widely in plants, fungi and algae. It is extracted mainly from seaweeds. It is used in food for diabetic patients as it is absorbed slowly. It is commonly used as a stabilizer, humectant, nutritive sweetener and bulking agent in food._x000D_ Application_x000D_ D-Mannitol has been used:_x000D_ • as a hydroxyl radical inhibitor, to detect the hydroxyl radical generation during the reactive oxygen species (ROS) modification of chromatin_x000D_ • in [3H]-mannitol permeability assay and also as a component in buffer B for measuring the transmonolayer dilution potentials_x000D_ • as a component in extracellular recording solution for whole cell patch clamp recordings_x000D_ Packaging_x000D_ 1 kg in poly bottle_x000D_ 250 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ D-Mannitol is used as an osmotic agent for the treatment of brain swellings._x000D_ A sugar alcohol sweet tastant. Used in sweetness inhibition studies._x000D_ Other Notes_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M9546.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.